Glycemic control metrics in a cohort of hospitalized patients with type 1 diabetes using hybrid closed-loop and advanced hybrid closed-loop systems
Authors' conclusion
HCL/AHCL systems with active AM/SG in patients with T1D in the hospital environment leads to %TIR > 70 % in ranges of 70-180 mg/dL in patients without increasing hypoglycemia.
Study context
- Population
- Hospitalized patients with T1D using hybrid closed-loop (HCL)/advanced hybrid closed-loop (AHCL); 50 % women; mean age 49 years (IQR 39–62)
- Participants
- 24 patients
- Exposure
- AHCL with active SmartGuard (SG) vs HCL with active Automated Mode (AM)
- Outcome
- Continuous glucose monitoring (CGM) metrics during hospital stay
- Follow-up
- During hospitalization
Main finding
As reported in the abstract
Patients achieving Time in Range (TIR) 70–180 mg/dL ≥ 70 %
70.8 %
Overall %TIR, median (IQR)
75.5 %
67.3–81.5 %
%time below range (TBR) < 70 mg/dL (IQR)
2.1 %
0.7–5.4 %
%TBR < 54 mg/dL (IQR)
0 %
0–5.4 %
Observational data: associations, not effects.
Further findings
%TIR during hospitalization, AHCL users with active SG vs HCL users with AM active · non-significant higher %TIR with AHCL + SG · sub-analysis
P = 0.312
Hospital LOS, AHCL users with active SG vs HCL users with AM active · shorter stay with AHCL + SG · sub-analysis
P = 0.045
Safety
- No device-related serious adverse events with either system
Original publication
Composed by AI from the published abstract and checked against it. How Briefs are made →