Glycemic Concordance of Simplera Sync ™ and Instinct ™ Sensors in MiniMed ™ 780G System Users: A Randomized Crossover Feasibility Study
Primary result · TIR (70-180 mg/dL)Result — go to the resultMean difference 1.5 % 95% CI 0.18–2.79Authors' conclusion
This randomized controlled crossover trial demonstrates that both Simplera Sync and Instinct sensors meet international consensus targets for glycemic control when used with the MM780G system, and that the sensors can be interchanged without meaningful differences in glycemic control.
Study context
- Population
- Adults with T1D using the MiniMed 780G system23 completed
- Participants
- 24 adults
- Comparison
- Simplera Sync vs Instinct sensor with MM780G
- Primary endpoint
- Noninferiority in time in range (TIR) (70-180 mg/dL), noninferiority margin 7.5%
- Follow-up
- 6-week sensor periods
Methodological detailssingle-center, two-arm, noninferiority, feasibility
- Single-center
- Two-arm
- Noninferiority
- Feasibility
Primary result
TIR (70-180 mg/dL) · 6-week period
Mean difference
1.5 %
95% CI 0.18–2.79
By group
Simplera Syncvs Instinct
mean difference 1.5 % (95% CI 0.18–2.79)
Non-inferiority margin 7.5 as printed, not drawn
As reported in the abstract
Secondary outcomes
HbA1c at end of sensor period · end of 6-week period
Safety
- Serious adverse events related to sensor use
- 0
Original publication
Glycemic Concordance of Simplera Sync ™ and Instinct ™ Sensors in MiniMed ™ 780G System Users: A Randomized Crossover Feasibility Study. Diabetes Technol Ther. Published 21 May 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →