Glycemic Outcomes and Device Engagement Over 18 Months Following Initiation of Two Different Automated Insulin Delivery Systems in American Youth With Type 1 Diabetes
Authors' conclusion
Although glycemic outcomes are similar between devices over 18 months, AID user engagement changes with time and differs between systems, potentially as they "trust" their device more. Change in carbohydrate entry among CIQ users is likely a major contributor to the decline in TIR with longer duration of AID use.
Study context
- Population
- US youth aged 6–18 with T1D starting automated insulin delivery (AID) between January 2020 and June 2024, large academic center; median age 14.3 years, median diabetes duration 5.5 years, 83.9% previous pump users
- Participants
- 722 participants
- Exposure
- Control IQ vs Omnipod 5 AID systems
- Control IQ (CIQ)n = 311
- Outcome
- Change in glycemic metrics (TIR) and user behaviors (self-initiated bolusing, carbohydrate entry) by system
- Follow-up
- 3, 6, 12 and 18 months
Methodological detailsreal-world, single academic centre, multivariable linear regression adjusted for baseline factors
- Real-world
- Single academic centre
- Multivariable linear regression adjusted for baseline factors
Main finding
As reported in the abstract
Change in TIR · 3, 6 and 18 months
- All AID users: change in time in range (TIR) across all time points
- >9.9% increase
- Change in TIR at 3 and 6 months, CIQ (greater)
- +14.9% and +13.3%
- Change in TIR at 3 and 6 months, OP5
- +10.0% and +10.2%
- Change in TIR at 18 months, CIQ
- +9.9%
- Change in TIR at 18 months, OP5
- +10.6%
Observational data: associations, not effects.
Further findings
Carbohydrate entry · 3, 6 and 18 months
- CIQ (decreased)
- 199, 184, and 173 g
- OP5 (not decreased)
- 177, 184, and 181 g
Original publication
Glycemic Outcomes and Device Engagement Over 18 Months Following Initiation of Two Different Automated Insulin Delivery Systems in American Youth With Type 1 Diabetes. Diabetes Technol Ther. Published 20 May 2026. doi:10.
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