Glucose sensor with predictive alarm for hypoglycaemia: Improved glycaemic control in adolescents with type 1 diabetes
Authors' conclusion
The use of RT-CGM with PA for hypoglycaemia technology in AwD using multiple daily insulin injection treatment could significantly reduce the risk of having hypoglycaemic events resulting in an improved quality of glucose control.
Study context
- Population
- Adolescents with T1Drandomised 1:1 to predictive alarm (PA)/Alarm on Threshold (AoT) or AoT/PA
- Participants
- 20 adolescents
- Comparison
- Real-time continuous glucose monitoring (RT-CGM) with predictive alarm vs alarm on threshold
- Primary endpoint
- %TBR <70 mg/dl
Methodological detailscrossover, monocentric
- Crossover
- Monocentric
Primary result
As reported in the abstract
PA
1.68
± 1.06
AoT
2.90
± 2.05
P < 0.02
Further findings
| Outcome | PA | AoT | P value |
|---|---|---|---|
| Severe hypoglycaemia %TBR2 <54 mg/dlLess time with PA | 0.32 ± 0.31 | 0.91 ± 0.90 | P < 0.02 |
| Glycaemia risk indexBetter with PA | 51.3 ± 11.0 | 61.5 ± 12.6 | P ≤ 0.01 |
Original publication
Glucose sensor with predictive alarm for hypoglycaemia: Improved glycaemic control in adolescents with type 1 diabetes. Diabetes Obes Metab. Published 4 January 2024. doi:10.
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