Glucose levels at hospital admission are associated with 5 year mortality
Authors' conclusion
Hyperglycaemia and hypoglycaemia on hospital admission are associated with increased long-term mortality.
Study context
- Population
- Patients admitted to hospital via the ED in a trial of glucose screening
- Participants
- 131,322 patients
- Comparison
- Admission glucose bands vs reference band 6.1-8.0 mmol/L
- Primary endpoint
- Long-term mortality
- Follow-up
- Up to 5 years after admission
Methodological detailsdeath registry linkage, Cox regression
- Death registry linkage
- Cox regression
Primary result
As reported in the abstract
Mortality · up to 5 years; mean follow-up 3.3 ± 1.5 years
Each group vs 6.1-8.0 mmol/LHazard ratio (95 % CI)P value
> 20.0 mmol/L
1.44(1.34–1.55)
P < 0.001≤ 4.0 mmol/L
1.56(1.46–1.68)
P < 0.001- Deaths overall
- 38,712 (29.5 %)
Further findings
| Outcome | HR (95 % CI) | P value | |
|---|---|---|---|
| Mortality, glucose ≥ 14.0 mmol/L: diabetes diagnosed during admissionvs not diagnosed | 0.53 (0.40–0.72) | P < 0.001 | |
| 0.512Hazard ratio (log scale) |
- Mortality, glucose ≥ 14.0 mmol/L: diabetes diagnosed during admission vs not diagnosed: n = 4867 with glucose ≥ 14.0 mmol/L; attenuated among 28-day survivors
Mortality among 28-day survivors
- Similar relationships were observed among 28-day survivors
Mortality among people with known diabetes
- Relationships were attenuated among people with known diabetes
Original publication
Glucose levels at hospital admission are associated with 5 year mortality. Diabetes Res Clin Pract. Published 30 August 2024. doi:10.
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