Global trends in the burden of chronic kidney disease attributable to type 2 diabetes: An age‐period‐cohort analysis
Authors' conclusion
After a lengthy period of multi-initiative diabetes management, the high-middle SDI region exhibited improvement. However, unresolved issues and improvement gaps were still remarkable. Future efforts to reduce the burden of CKD attributable to T2D in the population should prioritize addressing the unfavourable patterns identified.
Study context
- Population
- Global population and five sociodemographic index (SDI) regions, chronic kidney disease (CKD) attributable to T2D, 1990–2019
- Outcome
- Temporal trends of CKD attributable to T2D: DALYs, mortality, prevalence and incidence (net drifts, local drifts, longitudinal age curves, period and cohort RRs)
- Follow-up
- 1990 to 2019
Methodological detailsage-period-cohort modelling, global and five SDI regions
- Age-period-cohort modelling
- Global and five SDI regions
Main finding
As reported in the abstract
Burden of CKD attributable to T2D
- Global burden of CKD attributable to T2D showed increasing trends in general
- Burden highest in the middle SDI region and lowest in the low SDI region
- Age effects increased with age, peaking at ages 75-79 for incidence and 80-84 years for prevalence
- Period relative risks (RRs) increased; most remarkable in high SDI for disability-adjusted life years (DALYs) and mortality, most notable in middle SDI for incidence
- Cohort RRs showed unfavourable trends in incidence and prevalence among recent cohorts
Observational data: associations, not effects.
Original publication
Global trends in the burden of chronic kidney disease attributable to type 2 diabetes: An age‐period‐cohort analysis. Diabetes Obes Metab. Published 7 November 2023. doi:10. 1111/ dom. 15349
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