Global spatiotemporal Dynamics of Type 2 Diabetes Mellitus (T2DM) burden and projections: focusing on the impact of non-optimal temperature on adults aged 55+
Authors' conclusion
These findings highlight the growing disparities in T2DM burden across SDI levels
Study context
- Population
- Global T2D burden 1990–2021 across Socio-Demographic Index (SDI) levels, Global Burden of Disease (GBD) study
- Outcome
- T2D burden: mortality and DALYs
- Follow-up
- 1990-2021
Methodological detailsJoinpoint regression analysis, age-period-cohort modeling, decomposition analysis, projection model to 2044
- Joinpoint regression analysis
- Age-period-cohort modeling
- Decomposition analysis
- Projection model to 2044
Main finding
As reported in the abstract
Global T2D DALYs
Global T2D burden (Disability-Adjusted Life Years (DALYs)) increased modestly, annual average percent change (AAPC)
0.17 %
Low SDI regions, notable upward trend, AAPC
1.36 %
Observational data: associations, not effects.
Further findings
Projected T2D cases and DALY rates · through 2044
- Substantial rise across all age groups over 70, most significant increase in the 70-74 age group
Original publication
Global spatiotemporal Dynamics of Type 2 Diabetes Mellitus (T2DM) burden and projections: focusing on the impact of non-optimal temperature on adults aged 55+. Diabetes Res Clin Pract. Published 17 November 2025. doi:10.
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