Diabetes complications

Global prevalence of diabetes-related neuropathy and vascular complications: A systematic review and meta-analysis

Diabetes Res Clin PractPublished Systematic review and meta-analysis

Study context

Population
People with diabetes; studies from PubMed, Embase, Scopus, Web of Science and gray literature (Google Scholar, Garuda), searched to December 10, 2025155 studies
Outcome
Pooled prevalences of DPN and PAD
Methodological detailsmeta-regression
  • Meta-regression

Pooled result

As reported in the abstract

Pooled prevalence of diabetic peripheral neuropathy (DPN)

36 %

Pooled prevalence of peripheral artery disease (PAD)

19 %

Further pooled results

Prevalence by country development status

DPN prevalence, developed vs developing countries (higher in developing)
25 % vs. 39 %
PAD prevalence, developed vs developing countries (higher in developing)
10 % vs. 24 %

Chronic kidney disease (CKD) comorbidity and DPN prevalence (meta-regression)

CKD comorbidity associated with higher DPN prevalence, β
0.024 (95% CI 0.004-0.042)

DPN prevalence by assessment method

%

Combination method
39
Symptom assessment
36
Symptoms alone
30

Original publication

Global prevalence of diabetes-related neuropathy and vascular complications: A systematic review and meta-analysis. Diabetes Res Clin Pract. Published 12 January 2026. doi:10.1016/j.diabres.2026.113103

Composed by AI from the published abstract and checked against it. How Briefs are made →

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