Global and regional estimates of hip fracture burden associated with type 1 diabetes from 1990 to 2021
Authors' conclusion
High-income regions experienced the greatest burden of T1D-associated hip fracture, while Australasia and East Asia witnessed the largest increase over the last 32 years. Prioritizing the promotion of T1D treatment and hip-fracture screening for middle-aged females living with T1D is crucial in these regions.
Study context
- Population
- Adults aged ≥ 20 years with T1D, global, regional and national estimates, 1990–2021
- Outcome
- T1D-associated hip-fracture burden: incidence, age-standardized incidence rate (ASIR) and estimated annual percentage change (EAPC)
- Follow-up
- 1990 to 2021
Methodological detailspopulation attributable fraction, trend analysis (age-standardized incidence rate (ASIR), estimated annual percentage change (EAPC))
- Population attributable fraction
- Trend analysis (ASIR, EAPC)
Main finding
As reported in the abstract
Global T1D-related hip fractures · 2021
Global incidence
290 180
ASIR per 100 000 population
3.96
95% CI 1.92–5.87
Male-to-female ratio
0.54
Further findings
Super-regional burden: high-income regions · 2021
- Highest incidence, high-income regions
- 204 610
- Highest ASIR per 100 000 population (6.40-25.53), high-income regions, in particular Australasia and Western Europe
- 13.09
EAPC in T1D-associated ASIR · 1990 to 2021
- Australasia (highest)
- 2.90%
- East Asia
- 2.73%
Incidence among those aged 45-64 years · past decade
- Regions with significant growth
- 14
National ASIR trend · 1990 to 2021
- Countries with increased ASIR
- 166
Original publication
Global and regional estimates of hip fracture burden associated with type 1 diabetes from 1990 to 2021. Diabetes Obes Metab. Published 26 September 2024. doi:10.
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