Reproductive endocrinology

Gender Identity Milestones and Hormone Utilization in Transgender Men and Women in China

JAMA Netw OpenPublished Cross-sectional study

Authors' conclusion

In this cross-sectional study of Chinese TM and TW, gender identity development differed by gender, with TM recognizing incongruence earlier and TW progressing faster in initiating GAHT. Both groups showed strong demand for GAHT. Despite recent improvements in GAHT service accessibility, challenges persist in medical accessibility. These findings highlight the need for personalized support for transgender youths and underscore the importance of improving formal transgender health care services in China to enhance the well-being of this population.

Study context

Population
Transgender people in China, Chinese Transgender Health Survey, May–December 2021; median (IQR) age 21 (18–24) years
Participants
4,296 people
Exposure
Transgender men vs transgender women
  • Transgender men (TM)n = 1,462
  • Transgender women (TW)n = 2,834reference
Outcome
Timing of gender identity development milestones (first perception of gender incongruence, confirmation, disclosure, initiating GAHT) and GAHT utilization status
Methodological detailsonline snowball sampling, Chinese Transgender Health Survey 2021
  • Online snowball sampling
  • Chinese Transgender Health Survey 2021

Main finding

As reported in the abstract

Age at gender identity development milestones
Age at first perception of gender incongruence, median (IQR), TM vs TW
6 (4-10) years vs 9 (6-12) years
Age at confirmation, median (IQR), TM vs TW
14 (11-16) years vs 15 (12-17) years
Age at disclosure, median (IQR), TM vs TW
16 (14-19) years vs 17 (15-20) years
Age at initiating gender-affirming hormone therapy (GAHT), median (IQR), older in TM than TW
19 [17-22] years vs 18 [16-21] years
Demand for GAHT
3759 participants [87.5%]
GAHT usage
2247 participants [52.3%]
Valid prescriptions among hormone users
339 participants [15.1%]

Observational data: associations, not effects.

Further findings

Factors associated with GAHT-related behaviors and feedback (multivariable logistic regression)

Being TW and without college education associated with starting GAHT before age 16 years
Being TM, family disclosure of gender identity and official prescriptions associated with positive feedback on GAHT

Original publication

Gender Identity Milestones and Hormone Utilization in Transgender Men and Women in China. JAMA Netw Open. Published 2 January 2026. doi:10.1001/jamanetworkopen.2025.52440

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