Functional mobility and pain are improved for 6 years after adolescent bariatric surgery
Authors' conclusion
Adolescents who underwent MBS experienced significant, durable improvement in mobility and pain, despite weight regain. Our models suggest that improvements may occur through a weight-independent mechanism.
Study context
- Population
- Adolescents who underwent metabolic and bariatric surgery (MBS) (Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS))
- Exposure
- 6 years after MBS vs before surgery
- Outcome
- Change in mobility (400-m walk time, HR parameters) and musculoskeletal pain
- Follow-up
- 6 years
Methodological detailsTeen-LABS longitudinal study, mediation analysis
- Teen-LABS longitudinal study
- Mediation analysis
Main finding
As reported in the abstract
- Mean walk time, before surgery
- 383 s (95% CI 368-399)
- Mean walk time, by 6 years
- 351 s (95% CI 330-372)
- Mean resting HR, preoperatively
- 90 bpm (95% CI 87-93)
- Mean resting HR, by 6 years
- 80 bpm (95% CI 76-84)
- Risk of any musculoskeletal pain, before
- 37.2% (95% CI 25.5%-48.9%)
- Risk of any musculoskeletal pain, by 6 years
- 11.0% (95% CI 4.3%-17.6%)
Observational data: associations, not effects.
Further findings
Mediation analysis
- Effect of time since surgery on walk time, resting HR and HR recovery occurred through a weight-dependent mechanism
- Posttest HR and HR difference: both significant weight-dependent and weight-independent mechanism
- Effect of surgery on risk of musculoskeletal pain occurred through a weight-independent mechanism
Original publication
Functional mobility and pain are improved for 6 years after adolescent bariatric surgery. Obesity (Silver Spring). Published 21 April 2025. doi:10.
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