Frequency of brain ventricular enlargement among patients with diabetes mellitus
Authors' conclusion
Pathological ventricular enlargement is more frequent in men and in the elderly. In diabetic patients (especially women), the cerebral ventricles enlarge faster than in non-diabetic individuals. Age, sex, and diabetes may interact in determining how cerebral ventricle size changes over time, especially in diabetic women, making routine brain imaging advisable in these patients after the age of 70 years.
Study context
- Population
- Consecutive ED patients undergoing axial CT scans with a blood glucose measure1,221 scanned
- Participants
- 841 patients
- Exposure
- Diabetic vs not-diabetic patients
- Diabeticn = 104
- Outcome
- Prevalence of dilated ventricles (Evans' index >0.30) and concomitant high blood glucose
Methodological detailsconsecutive patients, emergency department database
- Consecutive patients
- Emergency department database
Main finding
As reported in the abstract
Dilated ventricles (EI > 0.30)
| Group | Value | Mean Evans' index (EI) among dilated |
|---|---|---|
| Diabetic | 24 % | 0.33 |
Diabetic
Value24 %
Mean Evans' index (EI) among dilated0.33
- Scans with EI > 0.30, all patients
- 176 (21 %)
Observational data: associations, not effects.
Further findings
Age difference between dilated and not-dilated ventricles
- Not-diabetic participants
- about ten years
- Diabetic participants
- five years
- Diabetic men
- about 10 years
- Diabetic women
- zero
Original publication
Frequency of brain ventricular enlargement among patients with diabetes mellitus. Diabetes Res Clin Pract. Published 27 March 2024. doi:10. 1016/ j. diabres. 2024. 111644
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