Type 2 & other diabetes

Frequency of brain ventricular enlargement among patients with diabetes mellitus

Diabetes Res Clin PractPublished Cross-sectional study

Authors' conclusion

Pathological ventricular enlargement is more frequent in men and in the elderly. In diabetic patients (especially women), the cerebral ventricles enlarge faster than in non-diabetic individuals. Age, sex, and diabetes may interact in determining how cerebral ventricle size changes over time, especially in diabetic women, making routine brain imaging advisable in these patients after the age of 70 years.

Study context

Population
Consecutive ED patients undergoing axial CT scans with a blood glucose measure1,221 scanned
Participants
841 patients
Exposure
Diabetic vs not-diabetic patients
  • Diabeticn = 104
Outcome
Prevalence of dilated ventricles (Evans' index >0.30) and concomitant high blood glucose
Methodological detailsconsecutive patients, emergency department database
  • Consecutive patients
  • Emergency department database

Main finding

As reported in the abstract

Dilated ventricles (EI > 0.30)
GroupValueMean Evans' index (EI) among dilated
Diabetic24 %0.33

Diabetic

Value24 %
Mean Evans' index (EI) among dilated0.33
Scans with EI > 0.30, all patients
176 (21 %)

Observational data: associations, not effects.

Further findings

Age difference between dilated and not-dilated ventricles

Not-diabetic participants
about ten years
Diabetic participants
five years
Diabetic men
about 10 years
Diabetic women
zero

Original publication

Frequency of brain ventricular enlargement among patients with diabetes mellitus. Diabetes Res Clin Pract. Published 27 March 2024. doi:10.1016/j.diabres.2024.111644

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