Osteoporosis, bone & mineral

Femoral neck width is associated with unique trajectories of age-related hip structural changes and fracture risk within populations of adult women and men

J Bone Miner ResPublished Pooled analysis of 4 longitudinal cohort studies

Authors' conclusion

Unique patterns of age-related structural changes with different biomechanical implications were identified within populations of women and men.

Study context

Population
Adult women and men with repeated hip DXA scans in 4 longitudinal studies4 longitudinal studies
Comparison
Larger vs smaller height-adjusted baseline FN area tertile
Outcome
Changes in FN BMC, area and aBMD across baseline FN area tertiles; hip fracture risk
Follow-up
10-15 yr
Methodological detailsrepeated hip DXA scans, 10-15 yr follow-up
  • Repeated hip DXA scans
  • 10-15 yr follow-up

Pooled result

As reported in the abstract

Likelihood of hip fracture (women)

2.5 times greater

Larger FN area tertile

Likelihood of hip fracture (men)

2.4-4.2 times greater

Larger FN area tertile

Original publication

Femoral neck width is associated with unique trajectories of age-related hip structural changes and fracture risk within populations of adult women and men. J Bone Miner Res. Published 28 June 2025. doi:10.1093/jbmr/zjaf090

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