Type 1 diabetes

Factors Affecting Reproducibility of Change in Glucose During Exercise: Results From the Type 1 Diabetes and EXercise Initiative

J Diabetes Sci TechnolPublished Secondary analysis of the T1DEXI study

Authors' conclusion

Reproducibility of change in glucose during exercise was low in this cohort of adults with T1D, but more consistency in pre-exercise glucose levels, IOB, and carbohydrates may increase this reproducibility. Mean glucose variability in the 24 hours after exercise is influenced more by the participant's overall glycemic control than other modifiable factors.

Study context

Population
Adults with T1D performing structured exercise sessions ≈30 minutes in lengthanalysed
Participants
476 adults
Primary endpoint
Within-participant reproducibility of glycemic response (change in glucose) during exercise

Primary result

As reported in the abstract

Change in glucose during exercise reproducible within 15 mg/dL of participant's other sessions

Proportion of time change in glucose during exercise was reproducible within 15 mg/dL

32%

Further findings

Variability of 24-hour post-exercise mean glucose

Lower mean glucose on sedentary days associated with less variable post-exercise mean glucose
P < 0.001
Lower glucose coefficient of variation (CV) on sedentary days associated with less variable post-exercise mean glucose
P < 0.001
Lower % time <70 mg/dL on sedentary days associated with less variable post-exercise mean glucose
P = 0.005

Original publication

Factors Affecting Reproducibility of Change in Glucose During Exercise: Results From the Type 1 Diabetes and EXercise Initiative. J Diabetes Sci Technol. Published 8 March 2024. doi:10.1177/19322968241234687

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