Exploring potential influencing factors of inadherence to specialist aftercare and long-term medication in patients with acromegaly
Authors' conclusion
To our knowledge, this is the first study which explored adherence to medication and aftercare in patients with acromegaly, taking into account potential influencing factors from all areas defined by the WHO model of adherence. Of the modifiable factors of adherence, patient-doctor relationship seemed to play a crucial role and could be one leverage point to improve adherence.
Study context
- Population
- Adults with acromegaly operated on a GH-producing pituitary adenoma >1 year ago, two tertiary treatment centres; 33 f, 30 m; mean age 56.1 yanswers analysed
- Participants
- 63 adults
- Exposure
- Patients with vs without adherence problems
- Outcome
- Factors associated with inadherence to aftercare and medication
Methodological detailspostal questionnaire, two tertiary centres
- Postal questionnaire
- Two tertiary centres
Main finding
As reported in the abstract
- Aftercare adherence problems vs adherent: significantly lower subjective symptom load
- p = 0.026
- Aftercare adherence problems vs adherent: lower perceived need for treatment
- p = 0.045
- Medication adherence problems vs none: higher subjective symptom load
- p = 0.056
- Medication adherence problems vs none: dissatisfied with consultation duration, 42% vs 4.8%
- p = 0.019
- Medication adherence problems vs none: tended to find physician explained potential adherence difficulties less well
- p = 0.089
Observational data: associations, not effects.
Original publication
Exploring potential influencing factors of inadherence to specialist aftercare and long-term medication in patients with acromegaly. Pituitary. Published 24 May 2024. doi:10.
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