Expert Consensus on the Primary Aldosteronism Severity Classification and its strategic application in indicating adrenal venous sampling
Authors' conclusion
Primary Aldosteronism Severity Classification is a newly developed simplified, semi-quantitative classification of PA severity. The correlation between PASC and lateralized PA subtype supports its potential to provide graded recommendations of AVS prior to surgical indication in each patient.
Study context
- Population
- Primary aldosteronism (PA) patients from 26 centers; classification developed by 45 international experts from 40 centers across four continents
- Participants
- 2,593 patients26 centers
- Comparison
- PA severity classes by Primary Aldosteronism Severity Classification (PASC)
- Outcome
- Distribution of PASC classes and lateralized subtype prevalence
Methodological detailsDelphi method, international, multicentre, Delphi panel of 45 international experts from 40 centers across four continents; four rounds
- Delphi method
- International
- Multicentre
- Delphi panel of 45 international experts from 40 centers across four continents; four rounds
Recommendations
As reported in the abstract
Values
Lateralized subtype prevalence
Original publication
Expert Consensus on the Primary Aldosteronism Severity Classification and its strategic application in indicating adrenal venous sampling. Eur J Endocrinol. Published 9 June 2025. doi:10.
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