Expected Basal Insulin Requirement During Continuous Subcutaneous Insulin Infusion Therapy by Age Group, Sex, and Body Mass Index, Based on 25,718 Young People with Type 1 Diabetes in the DPV Registry
Authors' conclusion
This analysis demonstrates multiple factors influencing basal patterns and insulin requirement, including age group, gender, overweight, HbA1c, bolus frequency, and sensor use.
Study context
- Population
- T1D patients aged 1–25 years on insulin pumps, DPV 2021 data pool; excluded night-time-only pump users, human regular insulin users and daily basal rates <0.05 and >1.0 U/(kgBW·d)
- Participants
- 25,718 patients
- Outcome
- Circadian basal rate patterns and total daily basal dose by age group, sex and BMI
Methodological detailsDPV registry, DPV 2021 data pool
- DPV registry
- DPV 2021 data pool
Main finding
As reported in the abstract
Basal rate patterns
- Significant differences in total daily basal dose between genders in all age groups except adults
- P < 0.001
Observational data: associations, not effects.
Original publication
Expected Basal Insulin Requirement During Continuous Subcutaneous Insulin Infusion Therapy by Age Group, Sex, and Body Mass Index, Based on 25,718 Young People with Type 1 Diabetes in the DPV Registry. Diabetes Technol Ther. Published 20 September 2023. doi:10.
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