Exercise-induced Changes in Central Adiposity During an RCT: Effect of Exercise Dose and Associations With Compensation
Authors' conclusion
In the presence of significant weight compensation, exercise at doses recommended for health and weight loss and weight maintenance leads to negligible changes in central adiposity.
Study context
- Population
- Adults with overweight or obesity (mean ± SD BMI 31.5 ± 4.7 kg/m²)randomized
- Participants
- 170 adults
- Comparison
- Exercise at 8 KKW or 20 KKW vs control
- Primary endpoint
- Change in central adiposity (waist circumference; VAT by DXA)
- Follow-up
- 6 months
Methodological detailsancillary analysis, 6-month
- Ancillary analysis
- 6-month
Primary result
As reported in the abstract
Change in waist circumference
Control
.0
95% CI −1.0–1.0 · cm
8 KKW
−.7
95% CI −1.7 to .4 · cm
20 KKW
−1.3
95% CI −2.4 to −.2 · cm
P ≥ 0.23
Further findings
| Outcome | Increase (cm) (95% CI) | P value | |
|---|---|---|---|
| Change in waist circumference: exercisers who compensatedvs those who did not · 6 months | 2.5 (.8 to 4.2) | P < 0.01 | |
| −20246Difference, cm (linear scale) |
| Outcome | Increase (kg) (95% CI) | P value | |
|---|---|---|---|
| Change in VAT: exercisers who compensatedvs those who did not · 6 months | .23 (.14 to .31) | P < 0.01 | |
| −0.200.20.4Difference, kg (linear scale) |
Weight compensation (weight loss less than expected) among exercisers · 6 months
- Exercisers who compensated
- 82.6%
Desire to eat as predictor of visceral adipose tissue (VAT) change during exercise
- β
- .21
- P
- P = 0.03
Original publication
Exercise-induced Changes in Central Adiposity During an RCT: Effect of Exercise Dose and Associations With Compensation. J Clin Endocrinol Metab. Published 29 November 2023. doi:10. 1210/ clinem/ dgad696
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