Excessive dietary sodium intake augments long-term risk of atrial fibrillation in older adults with hyperglycemia: A community-based prospective cohort study
Main finding · New-onset AFResult — go to the resultHazard ratio 1.525 95% CI 1.147–2.029Authors' conclusion
Our findings indicate that excessive sodium intake independently enhances the risk of new-onset AF among patients with hyperglycemia. A sodium-restricted diet may perhaps result in a multiplier effect on reducing the risk of new-onset AF.
Study context
- Population
- Community-dwelling adults aged ≥60 years with hyperglycemia, Shandong area, China, recruited April 2007–November 2011
- Participants
- 2,841 adults
- Exposure
- Excessive vs non-excessive dietary sodium intake
- Outcome
- New-onset AF (ICD-10 I48.0–I48.9)
Methodological detailscommunity-based
- Community-based
Main finding
New-onset AF
Hazard ratio
1.525
95% CI 1.147–2.029
adjusted P = 0.004
Excessivevs non-excessive dietary sodium intake
HR 1.525 (95% CI 1.147–2.029); adjusted P = 0.004
As reported in the abstract
Observational data: associations, not effects.
Further findings
New-onset atrial fibrillation (AF) per 1-SD increase in sodium intake
- HR per 1-SD increase in sodium intake (risk increased by 29.3%), adjusted P = 0.001
- 1.293 [1.108;1.509]
Interaction of excessive sodium intake with hyperglycemia on new-onset AF
- HR for interaction with fasting plasma glucose (FPG), adjusted P < 0.001
- 1.599 [1.342;1.905]
- HR for interaction with HbA1c, adjusted P < 0.001
- 1.516 [1.271;1.808]
- Synergistic interaction
Original publication
Excessive dietary sodium intake augments long-term risk of atrial fibrillation in older adults with hyperglycemia: A community-based prospective cohort study. Diabetes Metab. Published 5 September 2023. doi:10.
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