Type 1 diabetes

Excess mortality in type 1 diabetes patients in Belgium: A population based study

Diabetes Res Clin PractPublished Population-based cohort study

Authors' conclusion

Although our analysis showed a significantly lower excess mortality rate in T1D compared with older studies, a moderately increased excess risk of mortality is still shown. Given the continuous advances in diabetes treatment, it is important to perform further analyses to reassess the excess risk of mortality and to monitor this positive trend.

Study context

Population
Adult patients with T1D living and receiving treatment in Belgium, enrolled in the multidisciplinary care programme for diabetes self-management, 2017–2021
Participants
144,960 patient-years
Exposure
Adults with T1D vs general population
Outcome
Excess mortality and life expectancy vs the general population
Methodological detailsComorbidities identified by proxies based on health and/or medication use
  • Comorbidities identified by proxies based on health and/or medication use

Main finding

As reported in the abstract

Standardised mortality rate · 2017-2021

Standard mortality rate

1.21 (1.19;1.23) (95% CI)

Excess mortality rate

3.2 deaths per 1000 PY

Observational data: associations, not effects.

Further findings

Comorbidities

Renal insufficiency appeared to be the only comorbidity with a discernible effect on younger age groups

Original publication

Excess mortality in type 1 diabetes patients in Belgium: A population based study. Diabetes Res Clin Pract. Published 21 August 2025. doi:10.1016/j.diabres.2025.112426

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