Type 2 & other diabetes

Evidence of ethnic variations in the relationships between routinely recorded clinical factors and T2D: a systematic review and meta-analysis

Int J Obes (Lond)Published Systematic review and meta-analysis of observational studies

Authors' conclusion

Ratio measures of central adiposity may better identify T2D in ethnically diverse populations than measures of overall adiposity. Sex-specific factors must be considered when assessing T2D risk.

Study context

Population
Observational studies (1990–2023) of ethnic differences in routinely recorded demographic and clinical factors associated with T2D
Participants
10 332,949 participants54 studies
Comparison
Ethnic groups
Outcome
Association of overweight/obese BMI with T2D, by ethnicity
Methodological detailsrandom and fixed-effects meta-analysis, Risk of bias assessed with Newcastle-Ottawa Scale and Joanna Briggs Institute tool
  • Random and fixed-effects meta-analysis
  • Risk of bias assessed with Newcastle-Ottawa Scale and Joanna Briggs Institute tool

Pooled result

As reported in the abstract

White

4.85

OR · CI 3.53–6.68

Black

3.27

OR · CI 2.48–4.30

East Asian

3.06

OR · CI 2.29–4.16

Further pooled results

Association of waist-to-hip ratio (WHR) with T2D, by ethnicity

PopulationOR (CI)
Black2.74 (2.22-3.39)
White2.51 (2.30-2.74)

Women's health factors

Emerging importance of parity, birth weight and breastfeeding, especially among women of diverse ethnicities

Original publication

Evidence of ethnic variations in the relationships between routinely recorded clinical factors and T2D: a systematic review and meta-analysis. Int J Obes (Lond). Published 11 August 2025. doi:10.1038/s41366-025-01848-9

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