Evidence of ethnic variations in the relationships between routinely recorded clinical factors and T2D: a systematic review and meta-analysis
Authors' conclusion
Ratio measures of central adiposity may better identify T2D in ethnically diverse populations than measures of overall adiposity. Sex-specific factors must be considered when assessing T2D risk.
Study context
- Population
- Observational studies (1990–2023) of ethnic differences in routinely recorded demographic and clinical factors associated with T2D
- Participants
- 10 332,949 participants54 studies
- Comparison
- Ethnic groups
- Outcome
- Association of overweight/obese BMI with T2D, by ethnicity
Methodological detailsrandom and fixed-effects meta-analysis, Risk of bias assessed with Newcastle-Ottawa Scale and Joanna Briggs Institute tool
- Random and fixed-effects meta-analysis
- Risk of bias assessed with Newcastle-Ottawa Scale and Joanna Briggs Institute tool
Pooled result
As reported in the abstract
White
4.85
OR · CI 3.53–6.68
Black
3.27
OR · CI 2.48–4.30
East Asian
3.06
OR · CI 2.29–4.16
Further pooled results
Association of waist-to-hip ratio (WHR) with T2D, by ethnicity
| Population | OR (CI) | |
|---|---|---|
| Black | 2.74 (2.22-3.39) | |
| White | 2.51 (2.30-2.74) | |
| 0.20.5125Odds ratio (log scale) |
Women's health factors
- Emerging importance of parity, birth weight and breastfeeding, especially among women of diverse ethnicities
Original publication
Evidence of ethnic variations in the relationships between routinely recorded clinical factors and T2D: a systematic review and meta-analysis. Int J Obes (Lond). Published 11 August 2025. doi:10. 1038/ s41366-025-01848-9
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