Evaluation of a secondary care multidisciplinary clinic for adults with early‐onset type 2 diabetes at high risk in Leicester, Leicestershire and Rutland
Authors' conclusion
Case-finding and invitation to flexibly run multidisciplinary clinics were associated with improvements in cardiometabolic outcomes and positive patient feedback. Similar services are immediately required given the rising prevalence of EOT2D and associated complications.
Study context
- Population
- Adults with early-onset T2D at high risk (HbA1c >9%/triglyceride >20 mmol/L), Leicester, Leicestershire and Rutland, March 2024–September 2025; 45% women, median age 34 years
- Participants
- 159 adults
- Comparison
- 12 months vs baseline after multidisciplinary clinic
- Multidisciplinary clinicn = 159
- Outcome
- Change in cardiometabolic outcomes from baseline
- Follow-up
- 6 and 12 months
Methodological detailsbefore–after study, single-group, electronic medical records, paired t-test and McNemar's test
- Before–after study
- Single-group
- Electronic medical records
- Paired t-test and McNemar's test
Main finding
As reported in the abstract
Change from baseline in cardiometabolic outcomes · 12 months
- HbA1c change at 12 months
- −2.53% [−3.13, −1.93]/−28 mmol/mol [−34, 21] (95% CI)
- Systolic BP change
- −5.89 mmHg [−9.88, −1.91]
- Diastolic BP change
- −2.72 mmHg [−5.34, −0.10]
- Body mass index (BMI) change
- −1.49 kg/m² [−2.31, −0.67]
- Weight change
- −3.52 kg [−6.32, −0.72]
- Triglycerides change (lower at 12 months only)
- −1.12 mmol/L [−1.89, −0.34]
Further findings
Service activity: recording and prescriptions · 12 months vs baseline
- Higher proportion with BMI or smoking status recorded and with GLP-1 receptor-based treatment
- Creatinine and retinal screening measurements less frequent
Patient feedback
- A limited amount of patient feedback was positive
Original publication
Evaluation of a secondary care multidisciplinary clinic for adults with early‐onset type 2 diabetes at high risk in Leicester, Leicestershire and Rutland. Diabet Med. Published 30 April 2026. doi:10.
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