Evaluation of the Relationship Between Thyroid Hormone Levels and Bisphenol A in Children Aged 6−14 Years
Authors' conclusion
This study demonstrated that at least 50% of the children in the case group had bisphenol concentrations exceeding the highest value recorded in the control group, suggesting that total BP levels could be used as a potential biomarker for hypothyroidism.
Study context
- Population
- Children aged 6–14 years with newly diagnosed hypothyroidism and matched healthy controls
- Participants
- 51 vs 51
- Comparison
- Newly diagnosed hypothyroid children vs healthy controls
- Casen = 51
- Controln = 51reference
- Outcome
- Association between thyroid hormone levels and urinary bisphenol levels
Methodological detailsmatched
- Matched
Main finding
As reported in the abstract
Urinary bisphenol levels
| Group | Value | Median total concentration |
|---|---|---|
| Case | mean 16.5 ng/mL | 5.8 ng/mL |
Case
Valuemean 16.5 ng/mL
Median total concentration5.8 ng/mL
Observational data: associations, not effects.
Further findings
Diagnostic performance of bisphenol level >1.3 for hypothyroidism (ROC analysis)
- Sensitivity
- 83.7%
- Specificity
- 75%
Original publication
Evaluation of the Relationship Between Thyroid Hormone Levels and Bisphenol A in Children Aged 6−14 Years. Clin Endocrinol (Oxf). Published 2 March 2025. doi:10.
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