Obesity

Evaluation of clinical benefits and economic value of weight loss in a Swedish population using a simulation model

Obesity (Silver Spring)Published Simulation modelling study

Authors' conclusion

Annual treatment costs of ORCs in Sweden will double over 10 years, and weight loss would be associated with significant savings because of the reductions in the incidence of ORCs. Therefore, there is an urgent need to effectively treat obesity to prevent morbidity.

Study context

Population
2023 Swedish population with obesity aged 20 to 60 years; random cohort of 10,000 individuals simulatedmodelled cohort 10,000
Participants
887,272 participants
Comparison
Weight-loss scenarios vs stable weight
Outcome
Incidence of 10 obesity-related complications (ORCs) and treatment costs
Follow-up
10 years
Methodological detailsvalue of weight-loss simulation model, 10-year horizon
  • Value of weight-loss simulation model
  • 10-year horizon

Main finding

As reported in the abstract

Annual savings from prevented ORCs per 10,000 individuals · by 2033

Annual savings, 5% weight loss

9.0 million SEK/€0.8 million

Annual savings, 20% weight loss

30.0 million SEK/€2.6 million

Further findings

Prevalence of ORCs

Hypertension
24.1%
Asthma
20.9%
Dyslipidemia
18.3%
T2D
10.6%

Original publication

Evaluation of clinical benefits and economic value of weight loss in a Swedish population using a simulation model. Obesity (Silver Spring). Published 12 March 2025. doi:10.1002/oby.24232

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