Evaluating population attributable fractions of cardiovascular diseases in relation to 20-year body mass index; the ATTICA study (2002–2022)
Authors' conclusion
Future public health actions should not neglect to also include people with overweight for the effective management of body weight, which can offer significant long-term benefits for cardiovascular health. A graphical representation of the main study findings on population prevented and attributable fractions by long-term body weight status (n = 1348); the ATTICA study (2002-2022). CVD cardiovascular disease.
Study context
- Population
- Adults initially free of CVD from the ATTICA cohort study; mean age 39 (SD 10) years, 48% males
- Participants
- 1,348 adults
- Exposure
- Long-term body weight status and CVD
- Outcome
- PAF and PFP of combined fatal/non-fatal CVD cases by body weight trajectories
- Follow-up
- 2002–2022
Methodological details20-year follow-up (2002–2022)
- 20-year follow-up (2002–2022)
Main finding
As reported in the abstract
CVD cases prevented by maintaining normal body weight (prevented fraction for the population (PFP))
29%
95% CI 22%, 35%
CVD cases prevented if increased BMI (>25 kg/m²) eliminated
30%
8.7%, 38%
CVD cases prevented if overweight managed
23%
5.1%, 29%
CVD cases prevented if obesity managed
7.2%
1.1%, 9.1%
Observational data: associations, not effects.
Further findings
Population attributable fraction (PAFs) and PFPs by subgroup
- Variations of PAFs and PFPs by sex, age group, Mediterranean diet adherence, physical activity, comorbidities and anxiety trajectories
Original publication
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