Association between early age body mass index and the risk of adulthood cardiovascular diseases: a systematic review and meta-analysis
Authors' conclusion
We found a positive association between early-age BMI and adulthood cardiovascular diseases except for stroke.
Study context
- Population
- Studies of body mass index (BMI) in early age (age 2 to 22) in relation to adulthood CVD (CHD, ischemic and hemorrhagic stroke, MI, HF)38 studies
- Comparison
- Higher vs lower BMI in early age
- Outcome
- Adulthood CVD, including CHD, ischemic and hemorrhagic stroke, MI and HF
Methodological detailsfixed-effects and random-effects models
- Fixed-effects and random-effects models
Pooled result
As reported in the abstract
Association of early-age BMI with adulthood CVD
Early-age BMIHazard ratio (95% CI)
CVD
1.18(1.07–1.30)
CHD
1.13(1.07–1.19)
HF
1.16(1.11–1.20)
Stroke
0.99(0.93–1.05)
Further pooled results
Stratified analyses (sex, fatal/non-fatal events, socioeconomic status adjustment)
- Results remained consistent after stratification by sex, fatal or non-fatal events and adjustment for socioeconomic status
Age-specific analysis
- Both childhood and early adulthood showed positive associations with CHD and HF; estimates in early adulthood for all cardiovascular diseases (CVDs) numerically higher than for childhood
Category analyses (overweight or obesity)
- Positive association between overweight or obesity and adulthood CVDs, including stroke
Original publication
Association between early age body mass index and the risk of adulthood cardiovascular diseases: a systematic review and meta-analysis. Int J Obes (Lond). Published 15 January 2025. doi:10.
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