Endocrine oncology

Ethanol ablation of thyroid cysts in the young with a focus on efficacy and quality of life

Eur Thyroid JPublished Cohort study

Authors' conclusion

US-PEIT is a safe and effective method for the young, leading to improvements in cosmetic and subjective complaints, and should also be considered as first-line treatment in the young.

Study context

Population
Young patients aged 15–30 years with recurrent symptomatic thyroid cysts, 2015 to 2020; more women than men, mean age 23.8 years63 cysts
Participants
59 patients
Outcome
Cyst volume reduction, treatment failure and symptoms after US-PEIT
Follow-up
12 months

Main finding

As reported in the abstract

Mean cyst volume reduction ratio (about 1.5 mL injected alcohol)
90.7%
Single US-PEIT session undertaken
46%
Significant improvement in each symptom; total score difference
P < 0.001

Observational data: associations, not effects.

Further findings

Quality of life (QoL) by SF-36 vs age-corresponding norms · 6 months after last US-PEIT

Mean physical component summary, significantly different
56.5 (P < 0.001)
Mean mental component summary, not different
47.7 (P = 0.125)

Original publication

Ethanol ablation of thyroid cysts in the young with a focus on efficacy and quality of life. Eur Thyroid J. Published 11 August 2023. doi:10.1530/etj-23-0085

Composed by AI from the published abstract and checked against it. How Briefs are made →

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