Estimated small dense low-density lipoprotein-cholesterol and incident type 2 diabetes in Japanese people: Population-based Panasonic cohort study 13
Authors' conclusion
The estimated sd-LDL cholesterol was an important predictor of future incidence of diabetes within 10 years.
Study context
- Population
- Japanese participants of a Panasonic Corporation health checkup program, 2008–20186,080 developed T2D
- Participants
- 120,613 participants
- Outcome
- Incident T2D
Main finding
As reported in the abstract
10 years
AUC of estimated small dense low-density lipoprotein (sd-LDL) cholesterol for incident T2D
0.676
Optimal cut-off of estimated sd-LDL cholesterol
35.9 mg/dL
Observational data: associations, not effects.
Further findings
Lipid profiles and incident T2D (multivariate Cox analysis)
- LDL-C, HDL-C, TG, estimated lb-LDL cholesterol and estimated sd-LDL were associated with incident T2D
Original publication
Estimated small dense low-density lipoprotein-cholesterol and incident type 2 diabetes in Japanese people: Population-based Panasonic cohort study 13. Diabetes Res Clin Pract. Published 7 April 2023. doi:10. 1016/ j. diabres. 2023. 110665
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