Type 2 & other diabetes

Estimated small dense low-density lipoprotein-cholesterol and incident type 2 diabetes in Japanese people: Population-based Panasonic cohort study 13

Diabetes Res Clin PractPublished Population-based cohort study

Authors' conclusion

The estimated sd-LDL cholesterol was an important predictor of future incidence of diabetes within 10 years.

Study context

Population
Japanese participants of a Panasonic Corporation health checkup program, 2008–20186,080 developed T2D
Participants
120,613 participants
Outcome
Incident T2D

Main finding

As reported in the abstract

10 years

AUC of estimated small dense low-density lipoprotein (sd-LDL) cholesterol for incident T2D

0.676

Optimal cut-off of estimated sd-LDL cholesterol

35.9 mg/dL

Observational data: associations, not effects.

Further findings

Lipid profiles and incident T2D (multivariate Cox analysis)

LDL-C, HDL-C, TG, estimated lb-LDL cholesterol and estimated sd-LDL were associated with incident T2D

Original publication

Estimated small dense low-density lipoprotein-cholesterol and incident type 2 diabetes in Japanese people: Population-based Panasonic cohort study 13. Diabetes Res Clin Pract. Published 7 April 2023. doi:10.1016/j.diabres.2023.110665

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