Association between uric acid levels and incidence of type 2 diabetes: Population-based Panasonic cohort study 11
Authors' conclusion
Serum uric acid levels were associated with incident type 2 diabetes in Japanese women but not in Japanese men.
Study context
- Population
- Japanese participants of a Panasonic Corporation medical health checkup program, 2008–2018; 92,718 men and 29,405 women6,386 developed T2D
- Participants
- 122,123 participants
- Exposure
- Serum uric acid level categories
- Outcome
- Incident T2D
Main finding
As reported in the abstract
Incident T2D in women, by uric acid level
Each group vs uric acid ≤ 3 mg/dLHazard ratio (95 % CI)
Uric acid 5.1-6.0 mg/dL
2.01(1.26–3.42)
Uric acid > 6.1 mg/dL
1.85(1.11–3.22)
Observational data: associations, not effects.
Further findings
Uric acid for incident T2D at 10 years in women: AUC and optimized cut-off
- AUC
- 0.720
- Optimized cut-off
- 4.8 mg/dL
Original publication
Association between uric acid levels and incidence of type 2 diabetes: Population-based Panasonic cohort study 11. Diabetes Res Clin Pract. Published 24 November 2022. doi:10.
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