Endoscopic endonasal infrachiasmatic approach to intra-third ventricle craniopharyngiomas: surgical outcomes and limits to complete resection
Authors' conclusion
The EEIA may enable aggressive resection of IVCs while preserving and improving visual and cognitive function. Complete resection is limited by the geometry of the operative corridor and tumor adherence to vital structures.
Study context
- Population
- Patients with intra-third ventricle craniopharyngiomas (17 primary, 4 recurrent) treated with endoscopic endonasal infrachiasmatic approach (EEIA), 2016–202517 primary, 4 recurrent
- Participants
- 21 patients
- Outcome
- Extent of resection
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Gross total resection (GTR)
18 cases
Subtotal resection (STR)
3 cases
Observational data: associations, not effects.
Further findings
Improvement in preoperative impairment
- Visual improvement among those with preoperative visual impairment
- 69.2%
- Cognitive improvement among those with preoperative cognitive impairment
- 88.9%
Limits to complete resection
- Tumor margins beyond the anterior suprachiasmatic limit of the infrachiasmatic corridor (chiasma-clival line) limited safe dissection
- Tumor adherence to adjacent vasculature and mammillary bodies was an additional limitation
Original publication
Endoscopic endonasal infrachiasmatic approach to intra-third ventricle craniopharyngiomas: surgical outcomes and limits to complete resection. Pituitary. Published 9 July 2026. doi:10.
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