Empowering Diabetes Care Through Pharmacist-Led Education: A Randomized Controlled Trial in a Low-Resource Setting
Authors' conclusion
The pharmacist-led DSME program was effective in enhancing glycemic control, diabetes knowledge, self-management behaviors, and HRQoL in patients with T2DM. Findings from subgroup analyses underscore the potential of tailored pharmacist-led interventions to optimize outcomes in high-risk populations.
Study context
- Population
- Patients with T2D in a low-resource setting
- Participants
- 400 patients
- Comparison
- Pharmacist-led diabetes self-management education (DSME) vs standard care
- Primary endpoint
- Changes in HbA1c and diabetes knowledge (Michigan Diabetes Knowledge Test)
Methodological detailsparallel-group
- Parallel-group
Primary result
As reported in the abstract
- HbA1c in intervention group (IG), from 9.12% to 8.02%
- HbA1c in control group (CG), from 9.27% to 9.01%
- Diabetes knowledge score increased in IG (from 11.10 to 14.88); P < .001
- IG vs CG: P < 0.001
Secondary outcomes
Group × time interaction
- Significant group × time interaction for HbA1c and random blood glucose
Lipids and SBP in subgroup with elevated baseline levels
- Total cholesterol
- P = 0.03
- Triglycerides
- P = 0.04
- Low-density lipoprotein
- P = 0.03
- Systolic blood pressure
- P = 0.05
- Subgroup analysis
Self-management behaviors
- Significant gains with IG
- P < 0.001
Health-related quality of life (HRQoL)
- Significant gains with IG
- P < 0.001
Original publication
Empowering Diabetes Care Through Pharmacist-Led Education: A Randomized Controlled Trial in a Low-Resource Setting. Endocr Pract. Published 30 June 2025. doi:10. 1016/ j. eprac. 2025. 06. 022
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