Elective Aortic Surgery for Prevention of Aortic Dissection in Turner Syndrome: The Potential Impact of Updated European Society of Cardiology and International Turner Syndrome Consensus Group Guidelines on Referrals to the Heart Team
Authors' conclusion
New TS guidelines are likely to significantly increase the number of individuals with TS who might be considered for elective aortic surgery. Centres caring for individuals with TS should re-evaluate their TS cohorts for aortic dissection risk considering these new guidelines.
Study context
- Population
- Individuals with Turner Syndrome (TS) in a UK cohort
- Participants
- 156 individuals
- Outcome
- Proportion meeting updated guideline criteria for consideration of aortic surgery
Main finding
As reported in the abstract
Met updated guideline criteria for consideration of aortic surgery
21
13%
Additional individuals vs 2016 TS guideline criteria
15
Observational data: associations, not effects.
Further findings
Indexing methods
- Aortic size index (ASI) and aortic height index (AHI) together identified additional individuals meeting criteria vs ASI or AHI alone
- Z-score identified no additional individuals for surgical consideration and reclassified none into moderate or severe aortic dilation
Moderate aortic dilation meeting criteria for surgical consideration due to additional aortic dissection risk factors
- Moderate aortic dilation meeting criteria
- 12 of 13
Correlation of height or body surface area with ascending aorta diameter
- No positive correlation
Original publication
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