Elastography Enhances Diagnostic Accuracy of ACR TI-RADS in Thyroid Nodule Evaluation
Authors' conclusion
Integrating elastography into the ACR TI-RADS framework can optimize FNA utilization in the management of thyroid nodules by reducing the number of unnecessary aspiration biopsies.
Study context
- Population
- Adults with thyroid nodules ≥10 mm referred for fine-needle aspiration (FNA) per ACR TI-RADS; cytology by Bethesda system, surgical pathology as gold standard when available
- Participants
- 556 adults
- Comparison
- ACR TI-RADS plus elastography ratio thresholds vs ACR TI-RADS alone for FNA selection
- Outcome
- Number of FNA procedures with ER thresholds (>1.60, >0.44, >0.54 for ACR TI-RADS 3, 4, 5) as additional criterion
Performance
As reported in the abstract
- FNA procedures reduced from 501 to 260
- Without missing any malignant cases
Further findings
| Outcome | ACR TI-RADS + ER |
|---|---|
| Elastography discriminative performance in ACR TI-RADS 3 nodules | |
| Youden index | 0.994 |
| AUC | 0.994 |
Original publication
Elastography Enhances Diagnostic Accuracy of ACR TI-RADS in Thyroid Nodule Evaluation. J Clin Endocrinol Metab. Published 18 December 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →