Type 2 & other diabetes

The efficacy of resistance exercise training on metabolic health, body composition, and muscle strength in older adults with type 2 diabetes: A systematic review and Meta-Analysis

Diabetes Res Clin PractPublished Systematic review and meta-analysis of randomised trials

Pooled result · HbA1cResult — go to the resultMD −0.51

Authors' conclusion

These findings suggest that RET is beneficial for enhancing glycemic control, lipid profiles, lean mass, and muscle strength in older adults with T2DM, while its effects on body weight, fat mass, and cardiovascular health remain inconclusive.

Study context

Population
Older adults with T2D19 randomized controlled trials (RCTs)
Comparison
Resistance exercise training vs control
Outcome
HbA1c
Methodological detailsrandom-effects models, meta-regression
  • Random-effects models
  • Meta-regression

Pooled result

As reported in the abstract

MD

−0.51

P < 0.0001

Further pooled results

OutcomeMD (mg/dl)P value
Fasting blood glucose−1.43P = 0.04

Insulin levels

Insulin levels remained unchanged

Triglycerides

Significant reduction in triglycerides, MD (P = 0.03)
−0.32

Total cholesterol

Significant reduction in total cholesterol, MD (P = 0.005)
−7.08

LDL-C

Significant reduction in LDL-C, MD (P = 0.05)
−1.91

HDL-C

No significant change in HDL-C

Body composition

Resistance Exercise Training (RET) increased lean mass and reduced waist circumference; no effect on body weight and fat mass

Muscle strength, blood pressure and heart rate

Muscle strength improved significantly; no impact on blood pressure or heart rate

Original publication

The efficacy of resistance exercise training on metabolic health, body composition, and muscle strength in older adults with type 2 diabetes: A systematic review and Meta-Analysis. Diabetes Res Clin Pract. Published 14 March 2025. doi:10.1016/j.diabres.2025.112079

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