Obesity

Additional effects of exercise to hypocaloric diet on body weight, body composition, glycaemic control and cardio‐respiratory fitness in adults with overweight or obesity and type 2 diabetes: A systematic review and meta‐analysis

Diabet MedPublished Systematic review and meta-analysis

Authors' conclusion

Based on limited data, we did not find additional effects of exercise to hypocaloric diet in adults with overweight or obesity and type 2 diabetes on body weight, body composition or glycaemic control, while cardio-respiratory fitness improved.

Study context

Population
Adults with overweight or obesity and T2D11 studies
Comparison
Hypocaloric diet plus exercise vs hypocaloric diet alone
Outcome
Body weight, body composition, glycaemic control and cardio-respiratory fitness
Methodological detailsrandom-effects meta-analysis, Embase, Medline, Web of Science and Cochrane Central searched
  • Random-effects meta-analysis
  • Embase, Medline, Web of Science and Cochrane Central searched

Pooled result

As reported in the abstract

Change in body weight, body composition and glycaemic control
Not statistically different
Each group vs diet aloneEstimate (95% CI)
Diet + exercise
MD in change of body weight −0.77 kg(−2.03 to 0.50)
Diet + exercise
MD in change of fat-free mass −0.18 kg(−0.52 to 0.17)
Diet + exercise
MD in change of fat mass −1.61 kg(−4.42 to 1.19)
Not statistically different
Each group vs diet aloneMD in change of BMI, kg/m2 (95% CI)
Diet + exercise
−0.34(−0.73 to 0.05)
Not statistically different
Each group vs diet aloneMD in change of waist circumference, cm (95% CI)
Diet + exercise
−1.42(−3.84 to 1.00)
Not statistically different
Each group vs diet aloneMD in change of HbA1c, mmol/mol (95% CI)
Diet + exercise
−1(−3 to 1)
Not statistically different
Each group vs diet aloneMD in change of HbA1c, % (95% CI)
Diet + exercise
−0.1(−0.2 to 0.1)
Diet + exercise
MD in change of fasting glucose +0.14 mmol/L (95% CI −0.02 to 0.30)
Diet + exercise
MD in change of HOMA-IR +0.01 (95% CI −0.40 to 0.42)

Further pooled results

Significant increases in VO2max upon addition of exercise to hypocaloric diet
2 studies

Original publication

Additional effects of exercise to hypocaloric diet on body weight, body composition, glycaemic control and cardio‐respiratory fitness in adults with overweight or obesity and type 2 diabetes: A systematic review and meta‐analysis. Diabet Med. Published 26 April 2023. doi:10.1111/dme.15096

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