Resistance exercise training and its impact on metabolic syndrome in type 2 diabetes: A systematic review and meta-analysis of randomized controlled trials
Authors' conclusion
These findings suggest that RET is an effective intervention for improving MetS markers in individuals with T2DM.
Study context
- Population
- Patients with T2D; four databases searched up to September 2024
- Participants
- 2,271 patients50 randomized controlled trials (RCTs)
- Comparison
- Resistance exercise training vs control
- Resistance exercise training (RET)n = 1,186
- Controln = 1,085reference
- Outcome
- Metabolic syndrome markers
Methodological detailsrandom-effects models, High heterogeneity and small sample sizes noted as limitations
- Random-effects models
- High heterogeneity and small sample sizes noted as limitations
Pooled result
As reported in the abstract
- Reduction with RET
- MD (fasting blood glucose) −7.09 mg/dl; P < 0.00001
- Reduction with RET
- MD (TG) −14.05 mg/dl; P < 0.0001
- Reduction with RET
- MD (systolic blood pressure) −4.13 mmHg; P = 0.0004
- Reduction with RET
- MD (diastolic blood pressure) −2.03 mmHg; P = 0.02
- Reduction with RET
- MD (waist circumference) −2.18 cm; P < 0.00001
- Increase with RET
- MD (high-density lipoprotein) 1.86 mg/dl; P = 0.002
Further pooled results
Subgroups by intervention duration and gender
- Consistent benefits across varying intervention durations and participant genders
Original publication
Resistance exercise training and its impact on metabolic syndrome in type 2 diabetes: A systematic review and meta-analysis of randomized controlled trials. Diabetes Res Clin Pract. Published 8 March 2025. doi:10.
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