Efficacy of flash glucose monitoring on HbA1c in type 2 diabetes: An individual patient data meta-analysis of real-world evidence
Authors' conclusion
Commencement of flash glucose monitoring was associated with a significant reduction in HbA1c at 3-6 months in a real-world setting in T2DM managed with insulin.
Study context
- Population
- Adults with T2DM managed with insulin and baseline HbA1c 8.0 %-12.0 % (64–108 mmol/mol); mean age 62.8 years, BMI 32.2 kg/m²
- Participants
- 803 adults8 observational studies
- Comparison
- Before vs after commencing flash glucose monitoring
- Outcome
- Change in HbA1c
- Follow-up
- 3-6 months
Methodological detailsreal-world evidence, one-stage model
- Real-world evidence
- One-stage model
Pooled result
As reported in the abstract
HbA1c reduction
HbA1c reduction after commencing flash glucose monitoring, %
0.89 %
95% CI 0.71 to 1.08
HbA1c reduction, mmol/mol
9.8 mmol/mol
95% CI 7.8 to 11.8
Further pooled results
Heterogeneity between studies (one-stage model)
- Age, BMI and baseline HbA1c accounted for the substantial heterogeneity observed between studies
Baseline characteristics of included patients
- Age, mean (SD)
- 62.8(11.4) years
- BMI, mean (SD)
- 32.2(6.8) kg/m²
- Baseline HbA1c, mean (SD)
- 9.0(0.9) % [75 (10) mmol/mol]
Original publication
Efficacy of flash glucose monitoring on HbA1c in type 2 diabetes: An individual patient data meta-analysis of real-world evidence. Diabetes Res Clin Pract. Published 4 December 2024. doi:10.
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