Effects of the stress hyperglycemia ratio on long-term mortality in patients with triple-vessel disease and acute coronary syndrome
Main finding · Cardiovascular mortalityResult — go to the resultAdjusted hazard ratio 1.809 95% CI 1.160–2.822Authors' conclusion
The high level of SHR is associated with the long-term risk of cardiovascular mortality in TVD patients with ACS, and is confirmed to have incremental prediction value beyond standard SSII. Assessment of SHR may help to improve the risk stratification strategy in TVD patients who are under acute stress.
Study context
- Population
- Patients with triple-vessel disease (TVD) and acute coronary syndrome (ACS) with available baseline SHR measurement
- Participants
- 3,812 patients
- Exposure
- High vs median SHR
- Outcome
- Cardiovascular mortality
- Follow-up
- Median 5.1 years
Methodological detailstwo independent centers
- Two independent centers
Main finding
As reported in the abstract
Adjusted hazard ratio
1.809
95% CI 1.160–2.822
P = 0.009
High SHRvs Median SHR
aHR 1.809 (95% CI 1.160–2.822); P = 0.009
- Cardiovascular mortality, all TVD patients with ACS
- 219 (5.8%)
Observational data: associations, not effects.
Further findings
Prognostic value of SHR by diabetes status
- Prognostic value of SHR found exclusively among patients with diabetes, not those without diabetes
Model improvement vs SSII
- Addition of SHR improved the reclassification abilities of the SSII model for predicting cardiovascular mortality
Original publication
Effects of the stress hyperglycemia ratio on long-term mortality in patients with triple-vessel disease and acute coronary syndrome. Cardiovasc Diabetol. Published 25 April 2024. doi:10.
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