Effects of Qidan Tangshen Granule on diabetic kidney disease in patients with type 2 diabetes
Authors' conclusion
Qidan Tangshen Granule may be a potential therapeutic option for the treatment of DKD, offering improved clinical outcomes for patients.
Study context
- Population
- Patients with T2D and diabetic kidney disease (DKD)355 enrolled
- Participants
- 219 patients
- Comparison
- Qidan Tangshen Granule vs conventional treatment
- Interventionn = 109
- Controln = 110reference
Methodological detailsprospective, Follow-up at 3 and 12 months
- Prospective
- Follow-up at 3 and 12 months
Primary result
As reported in the abstract
Oxidative stress markers (SOD, 8-OHdG, 3-NT)
- Increased superoxide dismutase (SOD) and decreased 8-OHdG and 3-NT with intervention vs control, indicating reduced oxidative stress
Further findings
- Significant decrease in hemoglobin A1c (HbA1c) and UACR and improvement in glomerular filtration rate with intervention vs control
Original publication
Effects of Qidan Tangshen Granule on diabetic kidney disease in patients with type 2 diabetes. Diabetes Res Clin Pract. Published 2 February 2024. doi:10. 1016/ j. diabres. 2024. 111128
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