Diabetes complications

Effects of Qidan Tangshen Granule on diabetic kidney disease in patients with type 2 diabetes

Diabetes Res Clin PractPublished Randomised controlled trial

Authors' conclusion

Qidan Tangshen Granule may be a potential therapeutic option for the treatment of DKD, offering improved clinical outcomes for patients.

Study context

Population
Patients with T2D and diabetic kidney disease (DKD)355 enrolled
Participants
219 patients
Comparison
Qidan Tangshen Granule vs conventional treatment
  • Interventionn = 109
  • Controln = 110reference
Methodological detailsprospective, Follow-up at 3 and 12 months
  • Prospective
  • Follow-up at 3 and 12 months

Primary result

As reported in the abstract

Oxidative stress markers (SOD, 8-OHdG, 3-NT)
  • Increased superoxide dismutase (SOD) and decreased 8-OHdG and 3-NT with intervention vs control, indicating reduced oxidative stress

Further findings

Significant decrease in hemoglobin A1c (HbA1c) and UACR and improvement in glomerular filtration rate with intervention vs control

Original publication

Effects of Qidan Tangshen Granule on diabetic kidney disease in patients with type 2 diabetes. Diabetes Res Clin Pract. Published 2 February 2024. doi:10.1016/j.diabres.2024.111128

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