Effects of femoral neck width and hip axis length on incident hip fracture risk: a registry-based cohort study
Authors' conclusion
In conclusion, FNW is a risk factor for hip fracture before but not after adjustment for HAL. HAL, on the other hand, robustly and independently predicts hip fracture, including both FN and trochanteric fractures.
Study context
- Population
- Individuals with baseline hip BMD and hip geometry parameters, Province of Manitoba BMD registry; 90.8% women, mean age 64.7 yr
- Participants
- 75,095 individuals
- Exposure
- Per SD increase in femoral neck width (FNW) and hip axis length (HAL)
- Outcome
- Incident hip fracture (hospitalization with hip fracture as primary diagnosis)
- Follow-up
- Mean 8.3 (SD 5.1) yr
Methodological detailsregistry-based
- Registry-based
Main finding
As reported in the abstract
Incident hip fracture per SD increase
- Incident hip fractures recorded
- 2341
- FNW (age- and sex-adjusted), per SD: HR (95% CI); unchanged after adjustment for height, weight, FN BMD and clinical risk factors
- 1.15 (1.10-1.19)
- Correlation of FNW with HAL
- r = 0.68
- FNW further adjusted for HAL, per SD: HR
- 0.98 (0.94-1.03) (95% CI)
- HAL, per SD, adjusted for all covariates incl. FNW: HR
- 1.35 (1.28-1.42) (95% CI)
Observational data: associations, not effects.
Further findings
FN, intertrochanteric and non-hip fractures
- A similar pattern to hip fracture was seen for FNW
Original publication
Effects of femoral neck width and hip axis length on incident hip fracture risk: a registry-based cohort study. J Bone Miner Res. Published 27 January 2025. doi:10.
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