Effects of light‐intensity physical activity on cardiometabolic parameters in young adults with overweight and obesity: The SED ‐ ACT randomized controlled crossover trial
Authors' conclusion
Replacement and interruption of prolonged sitting with light-intensity walking showed a significant blood glucose-lowering effect and improved HRV during an 8-h work environment in young adults with overweight and obesity.
Study context
- Population
- Young adults with overweight and obesity; 8 women, mean age 23.4 ± 3.3 years, BMI 29.7 ± 3.8 kg/m², HbA1c 34.8 ± 3.1 mmol/mol [5.4 ± 0.3%]completed all four arms
- Participants
- 17 adults
- Comparison
- Alternate sitting and standing, continuous standing or continuous walking vs uninterrupted prolonged sitting during an 8-h simulated workday
- Primary endpoint
- Mean 8-h glucose
- Follow-up
- 8 h
Methodological detailsfour-arm
- Four-arm
Primary result
As reported in the abstract
8-h mean glucose
P = 0.034
- 8-h mean glucose lower in all other conditions vs sitting (SIT)
- P < 0.05
Secondary outcomes
| Outcome | Estimate | P value |
|---|---|---|
| 2-h postprandial glucose after breakfastWALK vs SIT · lower with WALK | ≈7% | P = 0.002 |
Heart rate variability (HRV) parameters
- Significant time × condition effects on HRV parameters favouring light-intensity walking
- P < 0.001
Original publication
Effects of light‐intensity physical activity on cardiometabolic parameters in young adults with overweight and obesity: The SED ‐ ACT randomized controlled crossover trial. Diabetes Obes Metab. Published 25 June 2024. doi:10. 1111/ dom. 15732
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