The effects of guar gum supplementation on glycemic control, body mass and blood pressure in adults: A GRADE-assessed systematic review and meta-analysis of randomized clinical trials
Pooled result · HbA1cResult — go to the resultWMD −0.47 mg/dL 95% CI −0.75 to −0.18Authors' conclusion
Guar gum supplementation may yield a beneficial effect on glycemic control in T2DM patients. However, the extant clinical trials, thus far, are not sufficient enough to form guidelines for clinical practice.
Study context
- Population
- Adults; Randomized Controlled Trials (RCTs) from PubMed, SCOPUS, Embase and Web of Science (inception to January 2022)14 RCTs
- Comparison
- Guar gum supplementation vs control
- Outcome
- Hemoglobin A1c (HbA1c)
Methodological detailsrandom-effects model, GRADE-assessed
- Random-effects model
- GRADE-assessed
Pooled result
As reported in the abstract
Weighted mean differences (WMD)
−0.47 mg/dL
95% CI −0.75 to −0.18
P = 0.001
Guar gumvs Control
WMD −0.47 mg/dL (95% CI −0.75 to −0.18); P = 0.001
Further pooled results
Fasting blood sugar (FBS), systolic and diastolic BP, body mass
- No effect on FBS, systolic and diastolic BP, and body mass vs control
FBS by subgroup (T2D; dose >15 g/d)
- Significant FBS decrease in T2D and with high dosages (>15 g/d), but not in other subgroups
Original publication
The effects of guar gum supplementation on glycemic control, body mass and blood pressure in adults: A GRADE-assessed systematic review and meta-analysis of randomized clinical trials. Diabetes Res Clin Pract. Published 22 March 2023. doi:10.
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