Osteoporosis, bone & mineral

Effects of an 18-month community-based, multifaceted, exercise program on patient-reported outcomes in older adults at risk of fracture: secondary analysis of a randomised controlled trial

Osteoporos IntPublished Secondary analysis of a randomised controlled trial

Authors' conclusion

This study supports the importance of adherence to exercise regimes, as adherence to the Osteo-cise: Strong Bones for Life program was associated with improvements in HRQoL and osteoporosis knowledge in older adults at increased risk for falls and fractures.

Study context

Population
Older adults aged ≥ 60 years with osteopenia or increased falls/fracture risk148 (91%) completed
Participants
162 adults
Comparison
Osteo-cise program vs control
  • Osteo-cisen = 81
  • Controln = 81reference
Primary endpoint
HRQoL (EQ-5D-3L), osteoporosis knowledge (Osteoporosis Knowledge Assessment Tool) and osteoporosis health beliefs (Osteoporosis Health Belief Scale)
Follow-up
12 and 18 months
Methodological details18-month, community-based
  • 18-month
  • Community-based

Primary result

As reported in the abstract

HRQoL, osteoporosis knowledge and health beliefs
  • No significant effects of the Osteo-cise program on health-related quality of life (HRQoL), osteoporosis knowledge or health beliefs relative to controls

Further findings

OutcomeP value
Per protocol (≥ 66% exercise adherence): EQ-5D-3L utility, net benefit · 12 monthsSignificant net benefitP = 0.024
Per protocol (≥ 66% exercise adherence): EQ-5D-3L utility, net benefit · 18 monthsSignificant net benefitP = 0.029
Per protocol (≥ 66% exercise adherence): osteoporosis knowledge scores, net improvement · 18 monthsSignificant net improvementP = 0.014
  • Per protocol (≥ 66% exercise adherence): EQ-5D-3L utility, net benefit: per protocol analysis; n = 41
  • Per protocol (≥ 66% exercise adherence): EQ-5D-3L utility, net benefit: per protocol analysis; n = 41
  • Per protocol (≥ 66% exercise adherence): osteoporosis knowledge scores, net improvement: per protocol analysis; n = 41

Adherence and attendance

Mean exercise adherence
55%
Mean attendance for the three osteoporosis educational sessions
63-82%

Original publication

Effects of an 18-month community-based, multifaceted, exercise program on patient-reported outcomes in older adults at risk of fracture: secondary analysis of a randomised controlled trial. Osteoporos Int. Published 2 March 2023. doi:10.1007/s00198-023-06693-y

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