Gestational diabetes & diabetes in pregnancy
Effectiveness of a Family-based Health Promotion Intervention for Women With Prior Gestational Diabetes Mellitus (GDM): The Face-It RCT
Authors' conclusion
The intervention did not result in lower BMI or increased quality of life but seemingly reduced other risk factors and lowered BMI in the subgroup of overweight women.
Study context
- Population
- Women with recent GDM, 3 sites in Denmarkrandomized 2:1
- Participants
- 277 women
- Comparison
- Family-based health promotion intervention vs usual care
- Interventionn = 184
- Usual caren = 93reference
- Primary endpoint
- Body mass index (BMI) and quality of life (SF12 MCS)
- Follow-up
- 1 year after delivery
Methodological detailsmulticenter, parallel, open-label, 2:1 allocation ratio
- Multicenter
- Parallel
- Open-label
- 2:1 allocation ratio
Primary result
As reported in the abstract
Each group vs usual careDifference in BMI, kg/m2 (95% CI)
Intervention
−0.44(−0.98 to 0.11)
Each group vs usual careDifference in SF12 MCS (95% CI)
Intervention
0.06(−2.15 to 2.27)
Further findings
| Outcome | Difference (kg/m²) (95% CI) | |
|---|---|---|
| BMI in women with BMI ≥25 kg/m² (prespecified post hoc analysis)Reduced BMI with intervention · prespecified post hoc analysis | −0.86 (−1.58 to −0.14) | |
| −2−101Difference, kg/m² (linear scale) |
| Outcome | Difference (pmmol/L) (95% CI) | |
|---|---|---|
| 2-hour insulin | −94.3 (−167.9 to −20.6) | |
| −200−1000100Difference, pmmol/L (linear scale) |
| Outcome | Difference (mmol/L) (95% CI) | |
|---|---|---|
| Triglycerides | −0.18 (−0.30 to −0.05) | |
| −0.4−0.200.2Difference, mmol/L (linear scale) |
| Outcome | OR (95% CI) | |
|---|---|---|
| FPG ≥6.1 mmol/L | 0.33 (0.12–0.91) | |
| 0.10.31310Odds ratio (log scale) |
Original publication
Effectiveness of a Family-based Health Promotion Intervention for Women With Prior GDM: The Face-It RCT. J Clin Endocrinol Metab. Published 9 December 2024. doi:10.
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