Effectiveness of lifestyle modification in prediabetes remission among women with isolated impaired fasting glucose: A community-based, randomised controlled trial in India
Primary result · Prediabetes remission (OGTT)Result — go to the resultRR for prediabetes remission 7.04 95 % CI 5.12–10.06Authors' conclusion
A structured LSM intervention effectively promotes prediabetes remission in women with i-IFG and improves cardio metabolic health.
Study context
- Population
- Women aged 30–60 years with isolated impaired fasting glucose (i-IFG), Kerala, India1,080 completed
- Participants
- 1,092 women
- Comparison
- 12-month lifestyle modification (LSM) program vs standard care
- Primary endpoint
- Prediabetes remission based on OGTT
- Follow-up
- 12 months
Methodological detailscommunity-based, parallel-group, open-label
- Community-based
- Parallel-group
- Open-label
Primary result
Prediabetes remission (OGTT)
RR for prediabetes remission
7.04
95 % CI 5.12–10.06
By group
LSMvs Standard care
RR for prediabetes remission 7.04 (95 % CI 5.12–10.06)
As reported in the abstract
- NNT for prediabetes remission
- 2.8 (1.8-4.0)
Secondary outcomes
Glycaemic, anthropometric and body composition changes
- Greater improvement with LSM in FPG
- −5.2 mg/dL
- Greater improvement with LSM in HbA1c
- −0.09 %
- Greater improvement with LSM in HOMA2-IR (log)
- −0.38
- Greater improvement with LSM in weight
- −3.7 kg
- Greater improvement with LSM in waist circumference
- −1.4 cm
- Greater improvement with LSM in fat mass
- −2.9 kg
- Greater improvement with LSM in fat-free mass
- +0.86 kg
Original publication
Effectiveness of lifestyle modification in prediabetes remission among women with isolated impaired fasting glucose: A community-based, randomised controlled trial in India. Diabetes Res Clin Pract. Published 13 January 2026. doi:10.
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