Effectiveness of educational and behavioural interventions for reducing fear of hypoglycaemia among adults with type 1 diabetes: Systematic review and meta‐analyses
Authors' conclusion
Current evidence suggests that educational and behavioural interventions can reduce fear of hypoglycaemia. However, no study to date has examined these interventions among people with high fear of hypoglycaemia.
Study context
- Population
- Adults with T1D5 randomized controlled trials (RCTs) (N = 682), 7 observational (N = 1519)
- Comparison
- Educational and/or behavioural interventions vs control
- Outcome
- Fear of hypoglycaemia (HFS-W and HFS-B subscales)
Methodological detailsrandom-effects meta-analyses of RCTs, narrative synthesis of observational studies, Risk of bias assessed with Joanna Briggs Institute Critical Appraisal Tools
- Random-effects meta-analyses of RCTs
- Narrative synthesis of observational studies
- Risk of bias assessed with Joanna Briggs Institute Critical Appraisal Tools
Pooled result
As reported in the abstract
Fear of hypoglycaemia (HFS-W and HFS-B scores); meta-analyses of RCTs
Significant effect of interventions on Hypoglycaemia Fear Survey Worry (HFS-W) scores, SMD
−0.17
p = 0.032
No significant effect of interventions on HFS-B scores, SMD
−0.34
p = 0.113
Further pooled results
Individual interventions across RCTs
- Blood Glucose Awareness Training (BGAT) had the largest effect on HFS-W and HFS-B scores
- One cognitive-behavioural therapy (CBT)-based program as effective as BGAT in reducing HFS-B scores
Observational studies
- Dose Adjustment for Normal Eating (DAFNE) associated with significant fear of hypoglycaemia reductions
Baseline fear of hypoglycaemia
- Mean fear of hypoglycaemia at baseline relatively low across studies
Original publication
Effectiveness of educational and behavioural interventions for reducing fear of hypoglycaemia among adults with type 1 diabetes: Systematic review and meta‐analyses. Diabet Med. Published 2 March 2023. doi:10. 1111/ dme. 15071
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