Diabetes technology

Effect of Low Bolus Frequency on Automated Insulin Delivery System Performance in Youth With Type 1 Diabetes

Diabetes CarePublished Retrospective cohort study

Main finding · Adjusted TIRResult — go to the resultDifference 8.0%

Authors' conclusion

Among AID users receiving ≤3.0 boluses/day, CIQ use was associated with greater TIR, likely due to increased time in AID and AID-initiated boluses.

Study context

Population
Youth with T1D using OP5 or Control-IQ (CIQ) averaging ≤3.0 boluses/day over 90 days98 matched for analyses
Participants
202 participants
Exposure
Tandem Control-IQ vs Omnipod 5 in youth with low bolus frequency
  • CIQn = 75
  • OP5n = 127reference
Outcome
Time in range (TIR)
Methodological detailspropensity-score matched
  • Propensity-score matched

Main finding

Adjusted TIR

Difference

8.0%

P = 0.002

By group

As reported in the abstract

Observational data: associations, not effects.

Further findings

Time in AID

P = 0.01

User-initiated boluses

No between-group difference in user-initiated boluses
2.2 boluses/day

Original publication

Effect of Low Bolus Frequency on Automated Insulin Delivery System Performance in Youth With Type 1 Diabetes. Diabetes Care. Published 11 December 2025. doi:10.2337/dc25-2082

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