Effect of gender on the evolution of pain and quality of life after treatment of symptomatic vertebral fragility fractures
Authors' conclusion
Pain and QoL evolution after a symptomatic VF differs according to gender, with a worse evolution in women independently of the treatment received.
Study context
- Population
- Patients with recent symptomatic vertebral fractures randomised to vertebroplasty vs conservative therapy; all received standardized analgesic and antiosteoporotic treatmentof 125 randomised
- Participants
- 118 patients
- Comparison
- Males vs females, after vertebroplasty or conservative therapy
- Malesn = 27
- Femalesn = 91
- Primary endpoint
- Evolution of pain (VAS) and QoL (Qualeffo-41) according to gender
- Follow-up
- Baseline, 2 weeks, 2 and 6 months
Primary result
As reported in the abstract
Pain and QoL evolution
- Pain and quality of life (QoL) evolution differed according to gender, being better in males; differences significant after two months independently of treatment and incidental vertebral fractures (VF) during follow-up
Further findings
| Outcome | Males | Females |
|---|---|---|
| Baseline VAS | 6.8 ± 2.1 | 6.8 ± 2.2 |
| Baseline Qualeffo score | 52.2 ± 24.4 | 59.7 ± 20.6 |
Baseline VAS
- No baseline differences
Baseline Qualeffo score
- No baseline differences
Original publication
Effect of gender on the evolution of pain and quality of life after treatment of symptomatic vertebral fragility fractures. Osteoporos Int. Published 30 November 2023. doi:10.
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