Osteoporosis, bone & mineral

Systematic review and meta-analysis of preoperative predictors for early mortality following hip fracture surgery

Osteoporos IntPublished Systematic review and meta-analysis of cohort studies

Authors' conclusion

This review found relevant preoperative predictors which could be used to identify patients who are at high risk of 30-day mortality following hip fracture surgery.

Study context

Population
Patients undergoing hip fracture surgery; cohort studies of independent preoperative predictors of mortality identified through Scopus and PubMed
Participants
462,699 patients33 cohort studies
Outcome
Predictors for 30-day mortality
Follow-up
30 days
Methodological detailsrandom-effects meta-analysis, GRADE assessment of evidence certainty, narrative synthesis of secondary outcomes
  • Random-effects meta-analysis
  • GRADE assessment of evidence certainty
  • Narrative synthesis of secondary outcomes

Pooled result

As reported in the abstract

Predictors of 30-day mortality (high-quality evidence)
Age per year, OR
1.06 (95% CI 1.04-1.07)
ASA score ≥ 3, OR
2.69 (95% CI 2.12-3.42)
Male gender, OR
2.00 (95% CI 1.85-2.18)
Institutional residence, OR
1.81 (95% CI 1.31-2.49)
Metastatic cancer, OR
2.83 (95% CI 2.58-3.10)

Further pooled results

Moderate-quality evidence predictors of 30-day mortality

Chronic renal failure, dementia, diabetes, low haemoglobin, heart failures and a history of any malignancy

Non-metastatic cancer · 30 days

Weak evidence as predictor of 30-day mortality

Original publication

Systematic review and meta-analysis of preoperative predictors for early mortality following hip fracture surgery. Osteoporos Int. Published 24 November 2023. doi:10.1007/s00198-023-06942-0

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