Effect of Exercise‐Induced Hormonal Changes on Skeletal Muscle Physiology
Authors' conclusion
The identified patterns are important for sports medicine, endocrinology, and rehabilitation, in particular, for maintaining muscle mass and correcting hormonal changes in different age groups.
Study context
- Comparison
- Strength training vs HIIT vs aerobic exercise
- Outcome
- Hormonal and physiological changes by training type
Methodological detailsHormones by laboratory biochemical assays; muscle mass, strength, endurance by clinical observation; ANOVA, t-tests, correlation analysis
- Hormones by laboratory biochemical assays; muscle mass, strength, endurance by clinical observation; ANOVA, t-tests, correlation analysis
Main finding
As reported in the abstract
Strength training: greatest increase in anabolic hormones, correlated with increased muscle mass
+12%
Strength training: increase in strength
+35%
Aerobic exercise: minor changes in anabolic hormones; significant increase in VO₂max
+30%
Aerobic exercise: increase in cortisol
+5%
Further findings
Myokines
- Changes in myokine levels, in particular irisin and osteocalcin
Age subgroups
- Anabolic response more pronounced in younger participants (18-35 years); muscle mass increase less significant in older groups (36-50 and 51-60 years)
Original publication
Effect of Exercise‐Induced Hormonal Changes on Skeletal Muscle Physiology. Clin Endocrinol (Oxf). Published 17 December 2025. doi:10.
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